Can Cannabis Transform Depression Therapy? A Critical Analysis

According to Statistics Canada’s Canadian Community Health Survey on Mental Health, 4.7% of Canadians aged 15+ experienced major depression. 

Nearly 1 in 8 adults (12.6%) reported experiencing a mood disorder at some point in their life, including 11.3% for depression.

Good news—researchers found a potential in various cannabis products to transform depression therapy. But how did scientific studies come to this conclusion? 

In this blog, we are going to talk about cannabis, its link to depression therapy, and how Burnaby weed delivery cannabis can help with the treatment. 

The Link Between Cannabis and Mental Health 

The interest surrounding weed for mental health is fueled by anecdotal reports and research. Studies found that alongside improvements in overall health-related quality of life and fatigue, patients experience reported notable reductions in symptoms of anxiety and depression. 

Medicinal Cannabis for Health-Related Quality of Life 

A study published from the PLOS ONE journal found that chronic health patients using medical cannabis saw improvements in health quality, fatigue, anxiety, depression, and pain over three months. 

Context and Survey

The study used responses from 2327 patients prescribed THC and CBD in MCT oil between November 2020 and December 2021. Patients reported on their health-related quality of life, pain, sleep, depression, and anxiety before starting cannabis therapy, after two weeks, and then monthly for three months.

Demographics and Outcomes

Of the surveyed patients, ranging from 18 to 97 years old, 11% were treated for depression and 22% for anxiety. Over three months, patients reported significant improvements in health-related quality of life and fatigue, as well as reductions in pain and improvements in moderate-severe anxiety and depression.

Effectiveness of Medical Cannabis for Treating Depression 

In this study published in the peer-reviewed journal Pharmacopsychiatry, they found that patients’ symptoms significantly improved. The severity of their depression notably decreased, with no severe side effects and a low dropout rate.

Study Highlights

Participants59 patients with chronic depression, unresponsive to traditional medications
TreatmentMedical marijuana flower over 18 weeks, starting in 2021. 
OutcomesSignificant improvement in depression severity.Average depression rating dropped from 6.9 to 3.8 over 18 weeks.23.7% of patients saw their depression severity halved in six weeks.Mild side effects in 35.6% of patients.No serious side effects or psychosis reported.Low dropout rate.
ConclusionThe treatment was safe and effective, with significant clinical improvements in depression.

Weed Possibilities in More Clinical Trials

A pilot study conducted by LVR University Hospital Essen in Germany showed promising results, with participants experiencing significant improvement in depression symptoms after using medical weed for 18 weeks.

Psychedelic-Assisted Therapy with Cannabis

Psychedelic-assisted therapy, particularly with psilocybin (magic mushrooms), has sparked interest in its potential to alleviate treatment-resistant depression. However, the conversation is expanding to include other high-quality products, including cannabis concentrates, CBD oil, edibles, pre-rolls, flowers, etc

Weed Components for Mental Health 

Cannabis or weed interacts with the body’s endocannabinoid system, receptors that take charge of regulating mood, pain, sleep, and other vital functions. The two main psychoactive compounds in cannabis produce their effects by influencing this system.

  • THC: THC is the central psychoactive component in cannabis products, responsible for the “high” feeling with recreational use. However, some research suggests THC may also have mood-altering properties.
  • CBD: CBD does not produce a “high” but has gained significant interest for its potential therapeutic effects. Studies suggest CBD may have anxiolytic (anti-anxiety) and mood-stabilizing properties.

Potential Mechanisms

Neurotransmitter Modulation

Cannabis may impact levels of serotonin and dopamine, which are responsible for mood regulation.

  • THC may increase dopamine levels, potentially elevating mood.
  • CBD may indirectly influence serotonin signalling.

Reduced Inflammation

Chronic inflammation has been bracketed to depression. Some studies suggest cannabis products may have anti-inflammatory properties, potentially contributing to mood improvement.

Key Aspects of Depression

  • Biological factors: Imbalances in neurotransmitters like serotonin and norepinephrine are thought to contribute to depression symptoms.
  • Psychological factors: Negative thought patterns, learned helplessness and past traumas can contribute to depression. Cognitive Behavioral Therapy is proven to be fruitful in addressing these patterns.
  • Social factors: Stressful life events, social isolation, and lack of social support can all trigger or worsen depression, which increase reliance on weed delivery in burnaby for immediate relief.
  • Medical conditions: Medical conditions like chronic pain, thyroid disorders, and even vitamin deficiencies can manifest with depression-like symptoms.

Traditional Depression Treatments vs. Cannabis

Aspect Traditional TreatmentCannabis 
Common Forms Antidepressants (SSRIs, SNRIs, MAOIs, TCAs), therapy (CBT, psychotherapy)Medical marijuana flower, CBD oil, THC oil
Effectiveness Varies; generally effective but may take weeks to months to see improvementsSome studies show significant improvement in weeks
Onset of ActionSeveral weeks to monthsNoticeable improvements within weeks
Treatment DurationLong-term, often indefiniteStudies typically over several months
Dropour RateModerate to high due to side effects or lack of efficacyLow dropout rate
Safety Generally safe but with a risk of serious side effects in some casesSafe with no serious side effects reported

Other Potential Benefits of Cannabis

Research suggests cannabis delivery driver may offer relief by interacting with the body’s endocannabinoid system. Studies have shown promise for using best cannabis delivery service to manage pain with conditions like:

  • Arthritis
  • Neuropathy
  • Migraines

For those with childhood-onset epilepsy syndromes, cannabidiol (CBD) shows promise in reducing seizure frequency. CBD is the psychoactive component responsible for the “high” associated with marijuana use.

Top Cannabis Products for Depression Therapy

Product NameTypeSizeBrandCBD ContentPrice
Raspberry Starry Night CBD Organic DarkBlend (Edible)1pcsThe Hazy Camper40.00%$6.00
CBN Bedtime Blueberry Lemon GummiesIndica (Edible)4pcsMonjour Bare80.00mg$10.00
Pomegranate 4:1 CBD/THCHybrid (Edible)5pcsPearls by Grön40.00mg/pack$6.00

Manage Depression with a Widest Selection of Cannabis in British Columbia

With the help of cannabis delivery in Burnaby, you can enhance your depression therapy 7 days a week with the wide selection of high-quality cannabis products, from cannabis oil, blend to hybrid new weed strains, concentrates, edibles, and more. 

Burnaby, BC has lots of weed stores offering free same-day weed delivery in Burnaby to make depression management easy for customers. 

So what are you waiting for? Purchase your reliable weed products now and have it delivered same-day 7 days a week! Buy weed and order online at the Sea to Sky Cannabis store for free same-day delivery service in Burnaby, BC.

Frequently asked questions

There are many different strains of cannabis, each with varying levels of THC (tetrahydrocannabinol) and CBD (cannabidiol), the two main cannabinoids that influence its effects for a few hours. Weed comes in three main types:

  • Sativa: Gives an uplifting, energetic feeling, good for daytime use.
  • Indica: Offers a relaxing, sedative effect, ideal for nighttime.
  • Hybrid: Combines traits of Sativa and Indica, providing a mix of effects.

Each type has different strains with unique qualities. Some are high in CBD, offering therapeutic benefits without making you feel high. Others have more THC, which gives the psychoactive effect.

Here are the categories of antidepressants that might interact with cannabis:

  • Selective Serotonin Reuptake Inhibitors: These amazing products are a common class of antidepressants that includes medications like fluoxetine (Prozac) and sertraline (Zoloft).
  • Serotonin-Norepinephrine Reuptake Inhibitors: This class includes medications like venlafaxine (Effexor) and duloxetine (Cymbalta).

Tricyclic Antidepressants: This is an older class less commonly prescribed today, but it’s still important to be aware of potential interactions. Amitriptyline (Elavil) is an example of a TCA.

According to the preamble of the College of Physicians & Surgeons of Alberta (CPSA), Health Canada registers individuals to use medical cannabis based on a document from a doctor or nurse. Professionals aren’t required to authorize weed, but if they decline, they must follow ethical guidelines. They must also follow laws like the Cannabis Act and Regulations. These rules outline how professionals can prescribe medical cannabis only to patients under their care. 

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