The Link Between Cannabis Terpenes and Pain Relief

Cannabis has been used for its medicinal properties for thousands of years, with modern research supporting its efficacy in pain management.

A study published in the Journal of Pain Research in 2020 found that 62.2% of medical marijuana users reported using weed to treat soreness, with a significant reduction in opioid use observed in 80.3% of participants.

Beyond cannabinoids like THC and CBD, terpenes—aromatic compounds found in the hemp plant—deliver therapeutic effects, particularly in analgesia. With the convenience of weed delivery, accessing terpene-rich weed strains for analgesic therapy has never been easier.

What are Cannabis Terpenes?

Terpenes are organic compounds produced by different plants, including cannabis. These compounds are important in plant biological functions and have implications for human health. 

They are responsible for plants’ characteristic aromas and flavours and contribute to the therapeutic effects of many cannabis products in any weed delivery service in Vancouver.

Valencene

Associated with anti-inflammatory and antihistaminic properties.

• Contributes to reducing inflammation and allergic responses.
• Applications in enhancing the flavour profile of weed strains.

Trans-Nerolidol

Known for its sedative and antimicrobial properties.

• Has been reported to exhibit sedative effects, making it useful for relaxation and sleep.
• Has antifungal and antibacterial properties.

Terpinolene

Has antioxidant and sedative properties.

• Calming and relaxing effects, which contribute to stress reduction and improved sleep.
• Has antioxidant properties that help protect cells from damage.

Phytol

Known for its anti-inflammatory and sedative properties.

• It may offer therapeutic benefits such as reduced inflammation and improved sleep quality.
• It also plays a role in the biosynthesis of cannabinoids.

Pinene

Has two isomeric forms: alpha-pinene and beta-pinene, known for its bronchodilator and anti-inflammatory properties.

• Enhance respiratory function and may counteract memory impairment associated with THC.
• Has potential anti-inflammatory and antimicrobial properties.

Myrcene

A monoterpene known for its sedative and muscle-relaxant properties.

• Induces a relaxing effect and enhance the sedative impacts of cannabis edibles.
• Increases the permeability of cell membranes, amplified by the THC.

Linalool

Known for its calming and anti-anxiety effects, and often used for its anxiolytic and sedative properties.

• Helps reduce stress and improve sleep efficiency
• Useful for managing anxiety.

Limonene

Includes mood-enhancing and anti-inflammatory responses.

• Elevates mood and reduce anxiety.
• Has anti-inflammatory properties, which is useful for alleviating conditions associated with inflammation.

Humulene

Commonly found in hops and coriander for energizing effects.

• Has anti-inflammatory and appetite-suppressant properties.
• ReduceS inflammation and may act as an appetite suppressant, which is beneficial for weight management.

Geraniol

Reminiscent of roses and is found in geraniums and citrus fruits, with antimicrobial and antioxidant properties.

• Contribute to improved skin health
• Also has calming results

Eucalyptol

Eucalyptol, also known as 1,8-cineole, is known for its respiratory and anti-inflammatory impacts.

• Helps alleviate respiratory issues and has inflammations.
• Often used in cough and cold remedies.

Delta-3-Carene

Delta-3-carene has a sweet, pine-like aroma, found in rosemary and basil.

• Contributes to reducing inflammation and promoting respiratory health.
• Aids in the relief of symptoms related to conditions like asthma.

Caryophyllene

Caryophyllene, also known as beta-caryophyllene, is unique among extracts for its ability to interact directly with CB2 receptors in the endocannabinoid system.

• Noted for its anti-inflammatory and analgesic properties.
• Helps manage discomfort and inflammation without causing psychoactive changes.

Camphene

Camphene has a strong, pungent aroma reminiscent of camphor.

• Used in traditional medicine for its antifungal and anti-inflammatory properties.
• Potential therapeutic applications in managing inflammation and fungal infections.

Borneol

Borneol has a camphor-like aroma and is found in various essential oils, including rosemary and mint. It is known for its sedative and analgesic reactions.

• Aid in palliative care and relaxation.
• Used in traditional medicine for its calming outcomes.

Bisabolol

Bisabolol is commonly found in chamomile, with anti-inflammatory and antimicrobial properties.

• Helps reduce inflammation and protect against infections
• Used in skincare for its soothing properties

How do Terpenes Act in Pain Relief?

Interaction with the Endocannabinoid System (ECS)

Terpenes modulate pain relief by interacting with the ECS in several ways:

1. Beta-caryophyllene interacts directly with CB1 receptors, which are primarily involved in modulating discomfort and analgesia.

• Beta-caryophyllene is unique as it can activate CB2 receptors without affecting CB1 receptors, thereby influencing nociception without psychoactive changes.

2. Beta-caryophyllene and humulene act on CB2 receptors, which are predominantly associated with anti-inflammatory responses.

• Activation of CB2 receptors can reduce inflammation and, consequently, distress. This interaction is particularly significant in managing conditions such as arthritis and other inflammatory disorders.

Research Evidence of Terpenes in Pain Relief

Comparative Efficacy of Terpenes and Morphine

A study published in the Journal of Cannabis Research in 2023 investigated the analgesic efficacy of various weed extracts compared to morphine. The researchers utilized animal models to evaluate the nociceptive response associated with their morphine administration.

• The study found that beta-caryophyllene and myrcene exhibited soothing results comparable to those of morphine. 
• In models such as the hot plate test and tail flick test, beta-caryophyllene reduced ache responses, indicating its potent analgesic properties.

Terpenes from Cannabis Sativa and Analgesic Results

Another 2020 study explored the analgesic outcomes of terpenes derived from Sativa. Researchers administered terpene extracts to animal models and assessed their impact on nociception. 

• The study identified myrcene, limonene, and linalool with notable analgesic impacts. 
• Myrcene demonstrated a reduction in inflammatory models, suggesting its efficacy in alleviating different conditions.
• The study emphasized the role of the “entourage effect,” where terpenes enhance or modulate the impacts of cannabinoids. 
• This interaction was evident in the combined administration of myrcene and THC, which resulted in enhanced mitigation compared to THC alone.

Top Weed Terpene-Rich Products

Product	Strain	Category	Terpenes	CBD Content	Price
Monsters Golden Guy Infused Pre-Roll	Sativa	Infused Pre-Roll	Bisabolol, Caryophyllene, Myrcene, Guaiol	0.00-20.00mg/g	$34.49 (1 x 2.38g)
Mango Haze 1:1 Balanced 510 Thread Cartridge	Blend	Vape	Caryophyllene, Pinene, Limonene, Linalool	400.00-460.00mg/g	$69.98 (2g)
Afghan Black Pressed Hash	Blend	Concentrate	Pinene, Caryophyllene, Myrcene, Linalool	0.00-10.00mg/g	$35.00 (2g)
GMO Cookies	Indica	Flower	Caryophyllene, Humulene, Limonene, Myrcene	0.00-10.00mg/g	$30.00 (3.5g)

Relieve Pain with Same Day Weed Delivery Products

The cannabis industry promotes the combination of terpenes and cannabinoids to enhance the overall therapeutic efficacy of weed edibles, pre-rolls, concentrates, and other forms of marijuana.

Since a more comprehensive and balanced approach is necessary, opting for a free weed delivery in British Columbia offers safe access to a great selection of weed products. 

From hybrid strains, pre-rolls, baked goods, and other products, you can buy weed online to satisfy your desired consumption methods and ensure you get the most effective solutions available.

For the best cannabis experience and benefits, browse Sea to Sky Cannabis’ products at great prices and have your weed delivered through our same-day weed delivery Vancouver service for your ultimate convenience.

You can also visit our cannabis dispensary and get assistance from our knowledgeable staff for a pain-free benefit from our premium cannabis products. Sea to Sky Cannabis is your top choice for a cannabis store near me, offering unmatched selection and service.